ISSN 2169-303X
International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 9 (4), pp. 001-004, April, 2020. © International Scholars Journals
Full Length Research Paper
Phytochemical Screening and antibacterial activity of extracts from Pakia Clapperotoniana keay against human pathogenic bacteria
D. Kubmarawa1*, M. E. Khan2, A. M. Punah1 and Hassan1
1Department of Chemistry School of Pure and Applied Sciences Federal University of Technology, P. M. B. 2076, Yola, Nigeria.
2Department of Chemistry Gombe State University, Gombe, Nigeria.
Accepted 15 November 2019
Abstract
Pakia clapperotoniana keay has medicinal properties for the effective management of several ailments including tuberculosis. To establish the pharmacological rationale, for its traditional use, the powdered root, stem- bark and leaves were extracted with water and ethanol. All fractions were subjected to phytochemical screening and antimicrobial activity against, Gram-positive and Gram-negative bacteria using the disc-diffusion method. The extracts contained saponnins, tannins, flavanoids, glycosides but no resin. The roots and stem-bark fractions were more active on Staphylococcus aureus, Streptococcus spp., Escherichia coli, Pseudomonas aeruginosa, Salmonella spp. and Baccilus subtilis, than the leaves fraction. These findings support the claim for its treatment of bacterial and fungal infections.
Key words: Pakia clapperotoniana keay, phytochemical, antimicrobial activity, Staphylococcus aureus, Escherichia coli.