ISSN 2169-303X
International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 9 (8), pp. 001-004, August, 2020. © International Scholars Journals
Full Length Research Paper
Antimicrobial activity of some plant extracts having hepatoprotective effects
Ammara Hassan, Salma Rahman, Farah Deeba and Shahid Mahmud
Applied Chemistry Research Centre, PCSIR Labs. Complex, Ferozpur Road, Lahore, Pakistan.
Accepted 19 July, 2020
Abstract
The antimicrobial activity of hot water and ethanolic extracts of six plant extracts, utilized in Pakistan for the cure of liver damage, were studied. The extracts of Acacia arabica, Nymphaea lotus, Sphareranthus hirtus, Emblica officinalis, Cinchorium intybus and Cardus marianum were tested in vitro against seven bacterial species and two fungal species by well-diffusion method and micro-dilution methods. The patterns of inhibition varied with the plant extracts, the solvent used for extraction and the organisms tested. Escherichia coli, Salmonella typhi, Pseudomonas aeroginosa were the most inhibited microorganisms. The extract of Sphareranthu hirtus was the most active against multi-drug resistant Pseudomonas aeruginosa and enterohemorrhagic E. coli 0157 EHEC. The ethanolic extract of S. hirtus exhibited a higher effect than the hot water extract. These plants extracts were analyzed for elemental composition.
Key words: Antimicrobial agents, plant extracts, Enterohemorrhagic Escherichia coli 0157 EHEC, multi-drug resistant Pseudomonas aeruginosa, Salmonella typhi, elemental composition.