ISSN 2326-7275
International Journal of Anatomy and Physiology ISSN 2326-7275 Vol. 12 (2), pp. 001-005, February, 2023. © International Scholars Journals
Full Length Research Paper
Exploring the effects of stress on white blood cell function in female wistar rats
A.I. Shugaba1*, S. A. Ojo2, A.S. Asala3, A.M. Rabiu4, C.B. Uzokwe1 and J.O. Hambolu2
1Department of anatomy, faculty of medical sciences, university of Jos, Nigeria.
2Department of vetinary anatomy, faculty of vetinary medicine, A.B.U. Zaria, Nigeria.
3Department of anatomy, college of health sciences, university of Abuja, Nigeria.
4Department of physiology, faculty of medical sciences, university of Jos, Nigeria.
Accepted 16 November, 2022
Abstract
The effect of induced physical and oxidative stress on the white blood cells (WBC) of female Wistar rats was investigated. 40 matured female Wistar rats were divided into four groups (A.B.C.D) ten per group. Group A, control, Group B, mono enucleation, Group C, bilateral enucleation and Group D, alcohol treated. The total and differential white cell counts were evaluated over the six weeks period of the induced stress. The results revealed no difference in the average total and differential white cell counts of the mono and bilaterally enucleated groups. While the alcohol treated group showed increase especially in the total WBC, neutrophils and eosinophils compared to the control group (P-value <0.05).
Keywords: Induced stress, Female Wistar rats, White blood cells (WBC)