ISSN 2375-1266
African Journal of Environmental and Waste Management ISSN 2375-1266 Vol. 11 (7), pp. 001-006, July, 2024. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Prevention of Chromium-Induced Cytogenetic Damage in Mouse Somatic Cells by Garlic Extract
Moshi Raju, K. Rudrama Devi* and Minny Jael. P
Human Genetics Lab., Department of Zoology, Osmania University.
Accepted 08 May, 2024
Abstract
The protective effect of garlic extract in chromium induced genotoxicity was evaluated using analysis of chromosomal aberrations in somatic cells of mice in IN VIVO animal model. Three doses of garlic extract were selected for modulation and were administered to animals after priming with chromium. All the animals were killed after 48 hrs of treatment and the mitotic preparations were made in somatic cells of mice. A significant decrease was observed in the percentage of chromosomal aberrations when animals primed with garlic extract. The present results clearly indicate the protective nature of garlic extract against heavy metal genotoxicity.
Keywords: Chromium, Chromosomal aberrations, Protection, Garlic extract.