ISSN 2736-1594
International Journal of Obstetrics and Gynecology ISSN 2736-1594 Vol. 8 (10), pp. 001-008, October, 2020. © International Scholars Journals
Full Length Research paper
Pregnancy outcome and neonatal health by mothers aged 40 years and over
Lorenza Driul1*, Ambrogio P Londero1*, Serena Bertozzi2*, Laura Peressini1, Michele Vanin1, Vito D’Aietti1, Arrigo Fruscalzo3, Anna Biasioli1, Stefania Salvador1, Riccardo Furlan4, Maria Maddalena Petrovec1, Diego Marchesoni1
1Clinic of Obstetrics and Gynecology, AOU "S M della Misericordia", 33100 Udine, Italy
2Clinic of Surgical Semeiotics, AOU "S M della Misericordia", 33100 Udine, Italy
3Department of Obstetrics and Gynecology, Gesundheitszentrum Rheine - Mathias-Spital, Rheine, Germany
4Neonatology Department, AOU "S M della Misericordia", 33100 Udine, Italy
Accepted 04 July, 2020
Abstract
This study was carried out to investigate obstetric outcomes in single pregnancies conceived by women older than 40 compared to those of their younger counterparts in a low natality setting with high mean age at first pregnancy. Data were collected about women who delivered in our Clinic between January and July 2005, excluding multiple pregnancies. Statistical analysis was performed using R (version 2.10.1), considering significant a p<0.05.We selected 688 women: 50 of them are 40 years or older and 638 are younger. Advanced age correlates with higher BMI (p=0.056) and seems to increase the risk of gestational hypertension (p<0.05) and gestational diabetes (p<0.05), cesarean sections (p<0.05) and vacuum extraction (p0.089), neonatal clavicle fracture (p<0.05) and perinatal mortality (p<0.05).Advanced age women have an increased risk of pregnancy complications, such as gestational hypertension and diabetes, neonatal clavicle fracture and perinatal death, and undergo more frequently cesarean sections.
Keywords: Advanced maternal age, pregnancy outcome, neonatal outcome, pregnancy related hypertensive disorders.